Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672648 | 0.85 | ALDH1A1 (0.43) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL13183725 | 0.84 | RAB9A (0.42) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28457016 | 0.84 | HSD17B10 (0.31) | PARP1KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL30068451 | 0.81 | CYP11B1 (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL21917644 | 0.79 | KDM4E (0.47) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL13183867 | 0.79 | TNKS (0.43) | PARP1SMN1; SMN2MPI | |
| SCHEMBL13183740 | 0.75 | NPC1 (0.41) | KDM4EALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL16796324 | 0.74 | CYP3A4 (0.39) | KDM4EALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL647671 | 0.74 | NISCH (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11032603 | 0.74 | F2 (0.47) | ESR1ESR2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11063228-B2 | Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200119288-A1 | Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues | UNITED STATES DEPARTMENT OF ENERGY | 2020-04-16 | — | — | US | disclosed |
| US-8519153-B2 | Compounds for fluorescent labeling | BROCK UNIVERSITY (CA) | 2013-08-27 | — | — | US | disclosed |
| US-8519153-B2 | Compounds for fluorescent labeling | BROCK UNIVERSITY (CA) | 2013-08-27 | — | — | US | disclosed |
| US-8519153-B2 | Compounds for fluorescent labeling | BROCK UNIVERSITY (CA) | 2013-08-27 | — | — | US | disclosed |
| US-20120071644-A1 | COMPOUNDS FOR FLUORESCENT LABELING | BROCK UNIVERSITY (CA) | 2012-03-22 | — | — | US | disclosed |
| US-20120071644-A1 | COMPOUNDS FOR FLUORESCENT LABELING | BROCK UNIVERSITY (CA) | 2012-03-22 | — | — | US | disclosed |
| US-20120071644-A1 | COMPOUNDS FOR FLUORESCENT LABELING | BROCK UNIVERSITY (CA) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200119288-A1 | Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues | IK, HELZ, SUN2 | ESR1 1898/4885ESR2 2252/4885PARP1 585/4885 |
| US-11063228-B2 | Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues | IK, HELZ, SUN2 | ESR1 1898/4885ESR2 2252/4885PARP1 585/4885 |
| US-20120071644-A1 | COMPOUNDS FOR FLUORESCENT LABELING | FBL, POLR1E, POLRMT | ESR1 2061/4885ESR2 1223/4885PARP1 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.