Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281274 | 0.94 | POLB (0.43) | MCHR1POLBKMT2AKDM4EMEN1 | |
| SCHEMBL28450962 | 0.94 | MCHR1 (0.47) | MCHR1POLBKMT2AKDM4EMEN1 | |
| SCHEMBL28451356 | 0.90 | MCHR1 (0.41) | MCHR1POLBKMT2AKDM4EMEN1 | |
| SCHEMBL21281165 | 0.88 | MCHR1 (0.44) | MCHR1POLBKMT2AKDM4EMEN1 | |
| SCHEMBL28073755 | 0.87 | MCHR1 (0.35) | MCHR1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL28074002 | 0.85 | KDM4E (0.40) | KDM4EMAPK1NCF1CYP1A2CYP2D6 | |
| SCHEMBL28459705 | 0.85 | ALDH1A1 (0.43) | POLBKMT2AKDM4EMEN1NPC1 | |
| SCHEMBL28449446 | 0.84 | MCHR1 (0.45) | MCHR1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL21281438 | 0.83 | KMT2A (0.44) | MCHR1POLBKMT2AKDM4EMEN1 | |
| SCHEMBL28459769 | 0.83 | ALDH1A1 (0.46) | POLBKMT2AKDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |