Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281165 | 0.95 | MCHR1 (0.44) | MCHR1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL28457357 | 0.94 | MCHR1 (0.43) | MCHR1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL28449446 | 0.91 | MCHR1 (0.45) | MCHR1NAMPTKDM4EMEN1MAPK1 | |
| SCHEMBL21281274 | 0.88 | POLB (0.43) | MCHR1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL28460462 | 0.88 | MCHR1 (0.46) | MCHR1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL28459705 | 0.85 | ALDH1A1 (0.43) | KDM4EMEN1KMT2AMAPTNPC1 | |
| SCHEMBL28073755 | 0.84 | MCHR1 (0.35) | MCHR1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL28451356 | 0.84 | MCHR1 (0.41) | MCHR1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL19901687 | 0.83 | AKR1C4 (0.39) | KDM4EMEN1MAPK1KMT2AMAPT | |
| SCHEMBL21281440 | 0.82 | MARS1 (0.43) | MCHR1KDM4EMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |