Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281274 | 0.89 | POLB (0.43) | KMT2AMEN1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL21281165 | 0.88 | MCHR1 (0.44) | KMT2AMEN1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL28457013 | 0.87 | TSHR (0.43) | KMT2AMEN1TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL21281440 | 0.85 | MARS1 (0.43) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28460807 | 0.84 | SMN1; SMN2 (0.46) | KMT2AMEN1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL19901693 | 0.83 | TP53 (0.37) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL19901700 | 0.83 | PDE4A (0.46) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21281197 | 0.83 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL19901697 | 0.83 | PDE4A (0.48) | KMT2ARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28457357 | 0.83 | MCHR1 (0.43) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552207-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2019-08-21 | — | — | EP | disclosed |