Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28698900 | 0.89 | BCL2A1 (0.40) | KDM4EALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL28710100 | 0.83 | APOBEC3A (0.36) | KDM4EALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL17981693 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1MAPTBCL2A1PTPN1 | |
| SCHEMBL28456400 | 0.78 | MPO (0.42) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL18723308 | 0.70 | MCHR1 (0.41) | KDM4EALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL21192138 | 0.69 | KMT2A (0.38) | KDM4EMAPTDHODH | |
| SCHEMBL15792448 | 0.68 | KDM4C (0.37) | KDM4EALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL18723313 | 0.67 | MPO (0.47) | MPODHODH | |
| SCHEMBL21176891 | 0.66 | TSHR (0.39) | ALDH1A1MAPTMAPK1BCL2A1PTPN1 | |
| SCHEMBL21180316 | 0.66 | CCNC (0.48) | KDM4EALDH1A1MAPTPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586272-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技股份有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-112979661-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-111615515-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-117586272-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-111615515-B | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-112979661-B | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-112979661-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-111615515-A | Heterocyclic compound, preparation method and application thereof in medicine | 苏州信诺维医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |