Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458103 | 0.83 | KDM4E (0.41) | ALDH1A1L3MBTL1KDM4EMAPK1PARP1 | |
| SCHEMBL28456400 | 0.79 | MPO (0.42) | ALDH1A1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL21120831 | 0.78 | MCHR1 (0.42) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL15792334 | 0.76 | ADORA2A (0.37) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28698900 | 0.75 | BCL2A1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL20116566 | 0.68 | KDM4E (0.40) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL21631385 | 0.66 | — | — | |
| SCHEMBL21192222 | 0.66 | MEN1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2TP53MEN1 | |
| SCHEMBL21192221 | 0.66 | TP53 (0.46) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL13699783 | 0.65 | GAA (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213331-B | URAT1 inhibitor and application thereof | 江苏新元素医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-108727267-B | URAT1 inhibitor and application thereof | 江苏新元素医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114213331-A | URAT1 inhibitor and application thereof | 江苏新元素医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |