Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458103 | 0.89 | KDM4E (0.41) | BCL2A1KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL28456400 | 0.79 | MPO (0.42) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL28710100 | 0.75 | APOBEC3A (0.36) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL17981693 | 0.72 | KDM4E (0.39) | BCL2A1KDM4EALDH1A1MAPTMPO | |
| SCHEMBL28454528 | 0.68 | BCL2A1 (0.42) | BCL2A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL17232702 | 0.66 | ADORA2A (0.62) | KDM4EMAPTMAPK1L3MBTL1RBP4 | |
| SCHEMBL13106216 | 0.66 | KDM4E (0.33) | KDM4EMAPTMAPK1L3MBTL1HTT | |
| SCHEMBL28461758 | 0.65 | BCL2A1 (0.54) | BCL2A1CYP3A4 | |
| SCHEMBL10642457 | 0.65 | RPS6KA5 (0.49) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL24045599 | 0.65 | ADORA2A (0.43) | KDM4EMAPTMAPK1L3MBTL1RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213331-B | URAT1 inhibitor and application thereof | 江苏新元素医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-108727267-B | URAT1 inhibitor and application thereof | 江苏新元素医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114213331-A | URAT1 inhibitor and application thereof | 江苏新元素医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |