Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | AOC1 | P19801 | 5/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PIEZO1 | Q92508 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844759 | 0.88 | GRIN1 (0.37) | LOXL2TRPV1KIF11ALDH1A1GRIN1 | |
| SCHEMBL17318488 | 0.82 | SCN9A (0.40) | LOXL2AOC1AOC3TRPV1KIF11 | |
| SCHEMBL805511 | 0.80 | ALDH1A1 (0.45) | LOXL2AOC1AOC3ALDH1A1LATS1 | |
| SCHEMBL25688536 | 0.80 | LOXL2 (0.38) | LOXL2AOC1AOC3TRPV1KIF11 | |
| SCHEMBL18986509 | 0.80 | LOXL2 (0.57) | LOXL2AOC1AOC3 | |
| SCHEMBL21503641 | 0.79 | PDE3B (0.39) | LOXL2AOC1AOC3ALDH1A1LATS1 | |
| SCHEMBL21503642 | 0.77 | CYP2E1 (0.44) | LOXL2AOC1AOC3ALDH1A1LATS1 | |
| SCHEMBL17981893 | 0.77 | LOXL2 (0.48) | LOXL2AOC1AOC3 | |
| SCHEMBL25673690 | 0.76 | RXRA (0.40) | LOXL2AOC1AOC3ALDH1A1SLC22A12 | |
| SCHEMBL24973994 | 0.75 | ALDH1A1 (0.34) | LOXL2AOC1AOC3ALDH1A1LATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111615513-A | C5a receptor modulators | 爱杜西亚药品有限公司 | 2020-09-01 | — | — | CN | disclosed |