Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453337 | 0.91 | TXNRD1 (0.41) | MAPTHTTTXNRD1GSRMERTK | |
| SCHEMBL28456869 | 0.87 | MAPT (0.37) | MAPTHTTALDH1A1DCTPP1TXNRD1 | |
| SCHEMBL28455076 | 0.83 | MAPT (0.41) | MAPTHTTTXNRD1GSRMERTK | |
| SCHEMBL28455078 | 0.83 | MAPT (0.41) | MAPTHTTTXNRD1GSRMERTK | |
| SCHEMBL28451066 | 0.80 | MAPT (0.41) | MAPTHTTALDH1A1DCTPP1SMN1; SMN2 | |
| SCHEMBL27931558 | 0.80 | CHRNB2 (0.40) | MAPTALDH1A1DCTPP1TXNRD1GSR | |
| SCHEMBL28450709 | 0.79 | POLB (0.41) | MAPTHTTALDH1A1DCTPP1SMN1; SMN2 | |
| SCHEMBL28454944 | 0.79 | TXNRD1 (0.40) | MAPTHTTTXNRD1GSR | |
| SCHEMBL27913490 | 0.78 | TXNRD1 (0.39) | MAPTALDH1A1DCTPP1TXNRD1GSR | |
| SCHEMBL28475797 | 0.77 | ALDH1A1 (0.38) | MAPTALDH1A1DCTPP1SMN1; SMN2TXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662283-A | Imidazopyridine compound and intermediate, preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-113480541-B | Process for producing imidazopyridine compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-111662283-B | Imidazopyridine compound and intermediate, preparation method and application thereof | 湖南化工研究院有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-113480541-A | Process for producing imidazopyridine compound and intermediate thereof | 湖南化工研究院有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-111662283-A | Imidazopyridine compound and intermediate, preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |