Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464635 | 0.88 | L3MBTL1 (0.49) | L3MBTL1MAPK1SERPINE1CNR1CNR2 | |
| SCHEMBL28463974 | 0.87 | LMNA (0.54) | L3MBTL1MAPK1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL28462858 | 0.87 | L3MBTL1 (0.55) | L3MBTL1MAPK1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL28462461 | 0.83 | L3MBTL1 (0.50) | L3MBTL1MAPK1SERPINE1CNR1CNR2 | |
| SCHEMBL28466891 | 0.82 | POLB (0.51) | L3MBTL1MAPK1SERPINE1SMN1; SMN2RXFP1 | |
| SCHEMBL28466895 | 0.80 | L3MBTL1 (0.55) | L3MBTL1MAPK1SMN1; SMN2RXFP1CNR1 | |
| SCHEMBL3105145 | 0.80 | SERPINE1 (0.59) | L3MBTL1MAPK1SERPINE1SMN1; SMN2RXFP1 | |
| SCHEMBL28899426 | 0.79 | HDAC1 (0.54) | L3MBTL1MAPK1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL28458204 | 0.79 | L3MBTL1 (0.55) | L3MBTL1MAPK1SMN1; SMN2CNR2NPSR1 | |
| SCHEMBL28455161 | 0.79 | L3MBTL1 (0.46) | L3MBTL1MAPK1SERPINE1SMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665985-B | Polysubstituted indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-09-29 | — | — | CN | disclosed |