Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462461 | 0.85 | L3MBTL1 (0.50) | L3MBTL1MAPK1CNR1CNR2ALDH1A1 | |
| SCHEMBL5210375 | 0.84 | POLB (0.53) | L3MBTL1MAPK1PLA2G2ACNR1CNR2 | |
| SCHEMBL28466891 | 0.84 | POLB (0.51) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28462854 | 0.80 | LTB4R (0.52) | L3MBTL1MAPK1PLA2G2ACNR1CNR2 | |
| SCHEMBL15712273 | 0.79 | LMNA (0.55) | PLA2G2AALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL28458491 | 0.79 | L3MBTL1 (0.50) | L3MBTL1MAPK1CNR1CNR2ALDH1A1 | |
| SCHEMBL28464635 | 0.78 | L3MBTL1 (0.49) | L3MBTL1MAPK1CNR1CNR2ALDH1A1 | |
| SCHEMBL28463974 | 0.77 | LMNA (0.54) | L3MBTL1MAPK1CNR1CNR2ALDH1A1 | |
| SCHEMBL15525164 | 0.77 | LMNA (0.51) | L3MBTL1MAPK1PLA2G2AALDH1A1LMNA | |
| SCHEMBL28462858 | 0.76 | L3MBTL1 (0.55) | L3MBTL1MAPK1CNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665985-B | Polysubstituted indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-09-29 | — | — | CN | disclosed |