Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940818 | 0.81 | L3MBTL1 (0.62) | L3MBTL1TDP1CTBP2RAB9ANPC1 | |
| SCHEMBL710924 | 0.81 | NPC1 (0.44) | L3MBTL1TDP1CTBP2RAB9ANPC1 | |
| SCHEMBL922780 | 0.80 | HTT (0.54) | TDP1CTBP2NPC1ALDH1A1CYP2C19 | |
| SCHEMBL1529438 | 0.80 | MCL1 (0.55) | L3MBTL1TDP1CTBP2ALDH1A1GAA | |
| SCHEMBL28166370 | 0.79 | ALDH1A1 (0.47) | L3MBTL1TDP1ALDH1A1GAATHRB | |
| SCHEMBL4852261 | 0.79 | CTBP2 (0.50) | L3MBTL1TDP1CTBP2NPC1ALDH1A1 | |
| SCHEMBL28458645 | 0.78 | CTBP2 (0.39) | L3MBTL1TDP1CTBP2RAB9ANPC1 | |
| SCHEMBL16746887 | 0.78 | LMNA (0.58) | HPGDALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL10520154 | 0.77 | CYP19A1 (0.42) | RAB9ANPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11470932 | 0.76 | CTBP2 (0.47) | L3MBTL1TDP1CTBP2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269247-B | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect | 河南科技大学第一附属医院 | 2020-11-24 | — | — | CN | claimed |
| CN-111269247-A | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect | 河南科技大学第一附属医院 | 2020-06-12 | — | — | CN | claimed |
| CN-111269247-B | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect | 河南科技大学第一附属医院 | 2020-11-24 | — | — | CN | disclosed |
| CN-111269247-B | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect | 河南科技大学第一附属医院 | 2020-11-24 | — | — | CN | disclosed |
| CN-111269247-A | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect | 河南科技大学第一附属医院 | 2020-06-12 | — | — | CN | disclosed |
| CN-111269247-A | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect | 河南科技大学第一附属医院 | 2020-06-12 | — | — | CN | disclosed |