Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 10/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28458359 | 1.00 | DNM1 (0.55) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL28464145 | 1.00 | DNM1 (0.55) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Hydrochloric Acid SCHEMBL6717011 | 0.96 | HTT (0.54) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL30402214 | 0.91 | DNM1 (0.52) | DNM1HTTHSP90AA1RAD52FAAH | |
| Hydrochloric Acid SCHEMBL10383871 | 0.91 | HTT (0.52) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Hydrochloric Acid SCHEMBL10384120 | 0.91 | HTT (0.52) | DNM1HTTHSP90AA1RAD52KMT2A | |
| SCHEMBL9408649 | 0.91 | HTT (0.50) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL1461564 | 0.87 | ALDH1A1 (0.52) | DNM1KMT2AFAAHSMN1; SMN2 | |
| SCHEMBL1462759 | 0.85 | SLC22A1 (0.50) | DNM1HSP90AA1KMT2AFAAHSMN1; SMN2 | |
| Iodide SCHEMBL1461547 | 0.84 | SLC22A1 (0.48) | DNM1HSP90AA1KMT2AFAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111748054-B | Acid-resistant resistance-reducing agent, preparation method thereof and acid-resistant slickwater fracturing fluid system | 中国石油天然气股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-111748054-A | Acid-resistant resistance-reducing agent, preparation method thereof and acid-resistant slickwater fracturing fluid system | 中国石油天然气股份有限公司 | 2020-10-09 | — | — | CN | disclosed |