Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100747 | 0.90 | EGFR (0.41) | EGFR | |
| SCHEMBL30467879 | 0.90 | EGFR (0.41) | EGFR | |
| SCHEMBL28457474 | 0.82 | UCHL3 (0.39) | UCHL3TGM2EGFRBTKFGFR4 | |
| SCHEMBL19100648 | 0.79 | EGFR (0.38) | EGFRBTK | |
| SCHEMBL19100693 | 0.77 | EGFR (0.38) | EGFR | |
| SCHEMBL17339175 | 0.76 | ALDH1A1 (0.34) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL17339171 | 0.76 | L3MBTL1 (0.33) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL19100682 | 0.72 | EGFR (0.43) | EGFR | |
| SCHEMBL28572522 | 0.70 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL19958220 | 0.70 | EGFR (0.54) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892579-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-111875585-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111892579-A | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111875585-A | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-106660993-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-09-11 | — | — | CN | disclosed |