Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824668 | 0.72 | PDE10A (0.31) | — | |
| SCHEMBL672555 | 0.61 | HRH4 (0.55) | HRH4CYP1A2 | |
| SCHEMBL12869079 | 0.60 | NOS3 (0.33) | CYP1A2TDP1 | |
| SCHEMBL11806912 | 0.58 | CYP1A2 (0.31) | CYP1A2TDP1 | |
| SCHEMBL12716504 | 0.58 | HRH4 (0.35) | HRH4 | |
| SCHEMBL4407459 | 0.57 | POLB (0.38) | HRH4 | |
| SCHEMBL1318068 | 0.56 | ALDH1A1 (0.42) | HRH4TDP1 | |
| SCHEMBL7930806 | 0.56 | ESR1 (0.39) | HRH4TDP1 | |
| SCHEMBL20313916 | 0.56 | NOS3 (0.33) | HRH4 | |
| SCHEMBL23026126 | 0.55 | CBLB (0.34) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712492-B | Cyclotriazoles as LPA antagonists | 百时美施贵宝公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-111712492-A | Cyclohexaneacetic acid triazolazoles as LPA antagonists | 百时美施贵宝公司 | 2020-09-25 | — | — | CN | disclosed |