Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318068 | 0.95 | ALDH1A1 (0.42) | ESR1GAATDP1ALDH1A1ALOX15 | |
| SCHEMBL4200442 | 0.75 | SLC6A2 (0.40) | ESR1GAATDP1ALDH1A1ALOX15 | |
| SCHEMBL1222163 | 0.75 | ESR1 (0.36) | ESR1HRH4LMNA | |
| SCHEMBL27985932 | 0.75 | ESR1 (0.33) | ESR1ALDH1A1LMNA | |
| SCHEMBL17563556 | 0.73 | ALDH1A1 (0.36) | ESR1GAATDP1ALDH1A1ALOX15 | |
| SCHEMBL12716504 | 0.70 | HRH4 (0.35) | ALDH1A1HRH4 | |
| SCHEMBL24799425 | 0.70 | NOS2 (0.48) | ESR1GAATDP1ALDH1A1ALOX15 | |
| SCHEMBL7400206 | 0.69 | ALDH1A1 (0.41) | TDP1ALDH1A1ALOX15TSHRLMNA | |
| SCHEMBL20313916 | 0.68 | NOS3 (0.33) | HRH4 | |
| SCHEMBL672555 | 0.68 | HRH4 (0.55) | TSHRHRH4LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239276-B1 | STABILIZER | CYTEC TECHNOLOGY CORPORATION | 2001-05-29 | — | — | US | disclosed |