Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458130 | 0.81 | USP2 (0.52) | USP2TP53RAB9AMAPK1KDM4E | |
| SCHEMBL28459155 | 0.76 | HTR7 (0.44) | USP2TP53RAB9AMAPK1KDM4E | |
| SCHEMBL29997186 | 0.75 | SCN8A (0.42) | TP53RAB9AMAPK1FFAR4KDM4E | |
| SCHEMBL29997699 | 0.70 | ALDH1A1 (0.43) | TP53RAB9AMAPK1KDM4EALDH1A1 | |
| SCHEMBL28460741 | 0.69 | FFAR4 (0.39) | LTB4RTP53RAB9AMAPK1FFAR4 | |
| SCHEMBL16982169 | 0.69 | FFAR4 (0.40) | FFAR4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8077098 | 0.68 | CNR2 (0.40) | ALDH1A1KMT2AMEN1HDAC3HDAC1 | |
| SCHEMBL28237730 | 0.68 | TP53 (0.53) | USP2TP53RAB9AMAPK1KDM4E | |
| SCHEMBL17667232 | 0.68 | TDP1 (0.45) | TP53ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL4254195 | 0.67 | ALDH1A1 (0.56) | TP53RAB9AMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108541-B | Method for producing butyrolactone compound | 日产化学工业株式会社 | 2020-06-19 | — | — | CN | disclosed |