Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.33 |
| ▸ | CDK2 | P24941 | 11/20 | 0.33 |
| ▸ | CCNH | P51946 | 10/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | CDK9 | P50750 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | INSRR | P14616 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23994152 | 0.73 | GSK3B (0.31) | GSK3B | |
| SCHEMBL2737272 | 0.70 | KDM4E (0.54) | — | |
| SCHEMBL1367838 | 0.69 | CDK7 (0.36) | CDK7CDK2CCNHMNAT1CCNE1 | |
| SCHEMBL1370649 | 0.69 | CDK2 (0.40) | CDK7CDK2CCNHMNAT1CCNE1 | |
| SCHEMBL24408250 | 0.69 | HAVCR2 (0.35) | CDK7CDK2CCNHMNAT1CCNE1 | |
| SCHEMBL26973993 | 0.68 | CDK2 (0.33) | CDK7CDK2CCNHMNAT1CCNE1 | |
| SCHEMBL23181411 | 0.68 | RAB9A (0.54) | CDK7CDK2CCNHMNAT1CCNE1 | |
| SCHEMBL20971704 | 0.68 | MAPT (0.54) | CDK7CDK2CCNHMNAT1CCNE1 | |
| SCHEMBL26974008 | 0.68 | CDK2 (0.40) | CDK7CDK2CCNHMNAT1CCNE1 | |
| SCHEMBL25590741 | 0.68 | KDM4E (0.37) | CDK7CDK2CCNHMNAT1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988172-B | Synthesis method of pyrazolo [1,5-A ] pyrimidine heterocyclic compound and derivative | 石家庄学院 | 2020-09-29 | — | — | CN | claimed |
| CN-109988172-B | Synthesis method of pyrazolo [1,5-A ] pyrimidine heterocyclic compound and derivative | 石家庄学院 | 2020-09-29 | — | — | CN | disclosed |