Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.33 |
| ▸ | CDK7 | P50613 | 10/20 | 0.33 |
| ▸ | CDK9 | P50750 | 6/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.33 |
| ▸ | CCNH | P51946 | 5/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.32 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | INSRR | P14616 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23547286 | 0.84 | CDK2 (0.32) | CDK2CDK7CDK9CDK5CCNH | |
| SCHEMBL23713346 | 0.82 | CDK2 (0.36) | CDK2CDK7CDK9CDK5CCNH | |
| SCHEMBL15245996 | 0.77 | CDK2 (0.40) | CDK2CDK7CDK9CDK5CCNH | |
| SCHEMBL25948858 | 0.76 | KDM4E (0.36) | — | |
| SCHEMBL20971704 | 0.74 | MAPT (0.54) | CDK2CDK7CDK9CDK5CCNH | |
| SCHEMBL2737272 | 0.73 | KDM4E (0.54) | — | |
| SCHEMBL26973961 | 0.72 | ALDH1A1 (0.40) | CDK2CDK9CCNE1MAPK1 | |
| SCHEMBL23547291 | 0.71 | CDK9 (0.35) | CDK2CDK7CDK9CCNHCCNE1 | |
| SCHEMBL26973963 | 0.71 | CDK2 (0.37) | CDK2CDK9CDK5CDK5R1CCNE1 | |
| SCHEMBL16659620 | 0.71 | MEN1 (0.46) | CDK2CDK7CDK9CDK5CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858937-B2 | Substituted pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a][1,3,5]triazines as CDK inhibitors | QURIENT CO., LTD. (KR) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858937-B2 | Substituted pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a][1,3,5]triazines as CDK inhibitors | CDKL5, CDK15, CDK5 | CDK2 9/4885CDK7 10/4885CDK9 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.