Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28465136 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4042473 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28455876 | 0.86 | ALOX15 (0.45) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL22042078 | 0.86 | CDK1 (0.58) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8324052 | 0.85 | XDH (0.55) | ALDH1A1KDM4EHPGDMAPTGLA | |
| SCHEMBL28464866 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL30055809 | 0.84 | HRH4 (0.53) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL21724772 | 0.84 | HRH4 (0.53) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8318032 | 0.83 | CDK1 (0.54) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28457805 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |
| CN-107098846-B | N-acyl sulfonamide FBPase inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |