Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786011 | 0.87 | ALDH1A1 (0.50) | KDM4EALDH1A1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL28466832 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1KMT2APAOX | |
| SCHEMBL22729319 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1KMT2APOLBCYP3A4 | |
| SCHEMBL28466833 | 0.82 | CYP3A4 (0.37) | KDM4EALDH1A1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL22729315 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1KMT2APOLBCYP3A4 | |
| SCHEMBL29169706 | 0.80 | ANPEP (0.45) | KDM4EALDH1A1KMT2APOLBMAPT | |
| SCHEMBL4140218 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1KMT2APOLBCYP3A4 | |
| SCHEMBL4149074 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1KMT2APOLBCYP3A4 | |
| SCHEMBL11237424 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1KMT2APOLBMAPT | |
| SCHEMBL28460427 | 0.77 | PABPC1 (0.34) | KDM4EALDH1A1KMT2APAOXADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3370863-B1 | METHOD FOR PRODUCING A CHROMATOGRAPHY MEDIUM | CYTIVA BIOPROCESS R & D AB (SE) | 2021-03-17 | — | — | EP | disclosed |