Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757143 | 0.82 | MEN1 (0.37) | GABRR1LMNASLC22A6CYP1A2GRIK1 | |
| SCHEMBL3783637 | 0.79 | GRM2 (0.36) | GRIK1SLC1A3SLC1A2SLC1A1GRM2 | |
| SCHEMBL3783644 | 0.79 | GRM2 (0.36) | GRIK1SLC1A3SLC1A2SLC1A1GRM2 | |
| SCHEMBL5582239 | 0.78 | KMT2A (0.37) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL10509551 | 0.77 | SLC22A6 (0.35) | GABRR1LMNASLC22A6SMN1; SMN2GRM8 | |
| SCHEMBL10508640 | 0.77 | SLC22A6 (0.35) | GABRR1LMNASLC22A6SMN1; SMN2GRM8 | |
| SCHEMBL27422541 | 0.77 | SLC22A6 (0.35) | GABRR1LMNASLC22A6SMN1; SMN2GRM8 | |
| SCHEMBL5658804 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2HIF1ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2807597 | 0.73 | GRIK1 (0.35) | GABRR1LMNASLC22A6HIF1AGRIK1 | |
| SCHEMBL7754149 | 0.73 | GRIK1 (0.35) | GABRR1LMNASLC22A6HIF1AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108744-B | anti-CD 123 Chimeric Antigen Receptor (CAR) for cancer therapy | 诺华股份有限公司 | 2020-09-25 | — | — | CN | disclosed |