Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807597 | 1.00 | GRIK1 (0.35) | GRIK1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL9655600 | 0.82 | GRIK1 (0.33) | GRIK1BHMT | |
| SCHEMBL18116107 | 0.80 | GRIK1 (0.38) | GRIK1BHMTGABRR1LMNASLC22A6 | |
| SCHEMBL12420389 | 0.80 | GRIK1 (0.38) | GRIK1BHMTGABRR1LMNASLC22A6 | |
| SCHEMBL10346841 | 0.80 | BHMT (0.33) | GRIK1TSHRBHMTCACNA2D1CACNB3 | |
| SCHEMBL10509551 | 0.78 | SLC22A6 (0.35) | GRIK1BHMTGABRR1LMNASLC22A6 | |
| SCHEMBL27422541 | 0.78 | SLC22A6 (0.35) | GRIK1BHMTGABRR1LMNASLC22A6 | |
| SCHEMBL10508640 | 0.78 | SLC22A6 (0.35) | GRIK1BHMTGABRR1LMNASLC22A6 | |
| SCHEMBL15976122 | 0.78 | ALDH1A1 (0.38) | GRIK1TSHRBHMTGABRR1LMNA | |
| SCHEMBL8695098 | 0.78 | SLC7A5 (0.54) | CACNA2D1CACNB3CACNA1CPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599483-A1 | 4-Phenylbutyric acid formulation | Lunamed AG (CH) | 2013-06-05 | — | — | EP | claimed |
| EP-0420539-A2 | Synergistic sweetening compositions containing a dipeptide sweetening agent and hydrogenated starch hydrolysates and methods for preparing same | WARNER-LAMBERT COMPANY (US) | 1991-04-03 | — | — | EP | claimed |
| EP-0256475-A2 | L-Aminodicarboxylic acid esters | GENERAL FOODS CORPORATION (US) | 1988-02-24 | — | — | EP | claimed |
| EP-2599483-A1 | 4-Phenylbutyric acid formulation | Lunamed AG (CH) | 2013-06-05 | — | — | EP | disclosed |
| EP-0691346-B1 | Novel aspartyldipeptide derivatives and sweetener | AJINOMOTO KK (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0818463-B1 | Aspartyl dipeptide amide derivatives and sweeteners | AJINOMOTO KK (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5958496-A | LOW CALORIE SWEETENING FOR FOOD, BEVERAGES; TASTE, STABILITY | AJINOMOTO CO., INC. (JP) | 1999-09-28 | — | — | US | disclosed |
| US-5723165-A | ARTIFICIAL SWEETENERS | AJINOMOTO CO., INC. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0818463-A1 | Aspartyl dipeptide amide derivatives and sweeteners | Ajinomoto Co., Ltd. (JP) | 1998-01-14 | — | — | EP | disclosed |
| EP-0691346-A1 | Novel aspartyldipeptide derivatives and sweetener | Ajinomoto Co., Inc. (JP) | 1996-01-10 | — | — | EP | disclosed |
| EP-0420539-A2 | Synergistic sweetening compositions containing a dipeptide sweetening agent and hydrogenated starch hydrolysates and methods for preparing same | WARNER-LAMBERT COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |
| EP-0398466-A2 | Synergistic sweetening compositions containing dipeptide sweetening agents and methods for preparing same | WARNER-LAMBERT COMPANY (US) | 1990-11-22 | — | — | EP | disclosed |
| US-4822635-A | Sweetening with L-aminodicarboxylic acid esters | GENERAL FOODS CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| US-4781927-A | Sweetening with l-aminodicarboxylic acid esters | GENERAL FOODS CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |