Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783644 | 1.00 | GRM2 (0.36) | GRM2GRM3SLC7A5CACNA2D1CACNB3 | |
| SCHEMBL3785917 | 0.83 | CYP1A2 (0.46) | GRM2GRM3SLC7A5BHMTSLC1A3 | |
| SCHEMBL3785916 | 0.83 | CYP1A2 (0.46) | GRM2GRM3SLC7A5BHMTSLC1A3 | |
| SCHEMBL7757143 | 0.81 | MEN1 (0.37) | GRM2GRM3BHMTSLC1A3SLC1A2 | |
| SCHEMBL28462913 | 0.79 | GABRR1 (0.31) | GRM2GRM3SLC1A3SLC1A2GRIK1 | |
| SCHEMBL3785075 | 0.74 | BHMT (0.35) | SLC7A5CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL3785078 | 0.74 | BHMT (0.35) | SLC7A5CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL5582239 | 0.74 | KMT2A (0.37) | GRM2GRM3SLC1A3SLC1A2GRIK1 | |
| SCHEMBL7754149 | 0.73 | GRIK1 (0.35) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL2807597 | 0.73 | GRIK1 (0.35) | CACNA2D1CACNB3CACNA1CPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3127737-A | — | — | None | — | — | JP | disclosed |
| JP-62151156-A | — | — | None | — | — | JP | disclosed |
| US-7846902-B2 | Dipeptide-comprising composition for oral administration | KYOWA HAKKO BIO CO., LTD. (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20080305151-A1 | Dipeptide-Comprising Composition for Oral Administration | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-12-11 | — | — | US | disclosed |
| EP-1941896-A1 | DIPEPTIDE-CONTAINING COMPOSITION FOR ORAL ADMINISTRATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| JP-H03127737-A | BRANCHED-CHAIN AMINO ACID PREPARATION | OTSUKA PHARMACEUT FACTORY INC | 1991-05-30 | — | — | JP | disclosed |
| JP-S62151156-A | NUTRIENT COMPOSITION | AJINOMOTO CO INC | 1987-07-06 | — | — | JP | disclosed |