Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190174 | 0.78 | HRH1 (0.46) | TAAR1HTR2ADPP4TSHRF2 | |
| SCHEMBL2376253 | 0.76 | TAAR1 (0.42) | TAAR1HTR2ADPP4TSHRF2 | |
| SCHEMBL27784141 | 0.75 | HTR2A (0.52) | TAAR1HTR2ADPP4TSHRF2 | |
| SCHEMBL15144138 | 0.74 | HRH1 (0.44) | TAAR1HTR2ADPP4TSHRF2 | |
| SCHEMBL4894981 | 0.74 | TAAR1 (0.40) | TAAR1HTR2ADPP4TSHRF2 | |
| SCHEMBL23343779 | 0.74 | TRPA1 (0.45) | TAAR1HTR2ADPP4TSHRF2 | |
| SCHEMBL10935767 | 0.74 | TAAR1 (0.40) | TAAR1HTR2ADPP4TSHRF2 | |
| SCHEMBL16377386 | 0.74 | TRPA1 (0.45) | TAAR1HTR2ADPP4TSHRF2 | |
| SCHEMBL367062 | 0.74 | LMNA (0.52) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL1567848 | 0.74 | TRPA1 (0.45) | TAAR1HTR2ADPP4TSHRF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678872-B | Bisbenzylisoquinoline compound and preparation method and application thereof | 山东师范大学 | 2020-09-29 | — | — | CN | disclosed |