SCHEMBL2376253

SCHEMBL2376253

ICC(I)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.42
HTR2A P28223 2/20 0.42
DPP4 P27487 2/20 0.39
TSHR P16473 2/20 0.39
F2 P00734 1/20 0.39
HRH1 P35367 2/20 0.39
MTOR P42345 1/20 0.39
RAB9A P51151 1/20 0.39
GRM7 Q14831 1/20 0.39
ALOX15 P16050 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 1/20 0.38
CASP1 P29466 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.37
CYP3A4 P08684 1/20 0.37
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31190174 0.80 HRH1 (0.46) TAAR1HTR2ADPP4TSHRF2
SCHEMBL17008844 0.79 HRH1 (0.41) TAAR1HTR2ADPP4TSHRF2
SCHEMBL7331209 0.77 HTR2A (0.52) TAAR1HTR2ADPP4TSHRF2
SCHEMBL16377386 0.76 TRPA1 (0.45) TAAR1HTR2ADPP4TSHRF2
SCHEMBL367062 0.76 LMNA (0.52) TAAR1HTR2AHRH1LMNA
SCHEMBL23343779 0.76 TRPA1 (0.45) TAAR1HTR2ADPP4TSHRF2
SCHEMBL28463171 0.76 TAAR1 (0.40) TAAR1HTR2ADPP4TSHRF2
SCHEMBL4894981 0.76 TAAR1 (0.40) TAAR1HTR2ADPP4TSHRF2
SCHEMBL15144138 0.76 HRH1 (0.44) TAAR1HTR2ADPP4TSHRF2
SCHEMBL10935767 0.76 TAAR1 (0.40) TAAR1HTR2ADPP4TSHRF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218913-B Porous body and method for producing porous body 株式会社伊玛尔斯京都 2023-10-27 CN disclosed
US-20230135119-A1 METHODS OF USING PROTEIN PALMITOYLATIONS INHIBITORS NATIONAL INSTITUTES OF HEALTH 2023-05-04 US disclosed
US-11613618-B2 Porous body, and method for producing porous body EMAUS KYOTO, INC. (JP) 2023-03-28 US disclosed
CN-113372235-B Process for preparing 1-amino-2-phenylcyclopropanecarboxylic acids 佛山奕安赛医药科技有限公司 2022-08-19 CN disclosed
CN-113372235-A Process for preparing 1-amino-2-phenylcyclopropanecarboxylic acid 佛山奕安赛医药科技有限公司 2021-09-10 CN disclosed
US-20210214514-A1 POROUS BODY, AND METHOD FOR PRODUCING POROUS BODY EMAUS KYOTO, INC. (JP) 2021-07-15 US disclosed
EP-3789444-A1 POROUS BODY, AND METHOD FOR PRODUCING POROUS BODY Emaus Kyoto, Inc. (JP) 2021-03-10 EP disclosed
WO-2021027210-A1 LUBRICATING OIL VISCOSITY INDEX MODIFYING AGENT CONTAINING STAR-SHAPED SEP COPOLYMER AND PREPARATION METHOD THEREFOR 深圳昆油石化技术有限公司 2021-02-18 WO disclosed
CN-112218913-A Porous body and method for producing porous body 株式会社伊玛尔斯京都 2021-01-12 CN disclosed
US-10858491-B2 Porous particle made of organic polymer, method for producing porous particle made of organic polymer, and block copolymer KYOTO UNIVERSITY (JP) 2020-12-08 US disclosed
EP-3327071-A1 POROUS PARTICLE MADE OF ORGANIC POLYMER, METHOD FOR PRODUCING POROUS PARTICLE MADE OF ORGANIC POLYMER, AND BLOCK COPOLYMER Kyoto University (JP) 2018-05-30 EP disclosed
EP-3327070-A1 POROUS PARTICLE, METHOD FOR PRODUCING POROUS PARTICLE, AND BLOCK COPOLYMER Kyoto University (JP) 2018-05-30 EP disclosed
EP-2330154-B1 AQUEOUS PIGMENT DISPERSION AND APPLICATIONS THEREOF DAINICHISEIKA COLOR CHEM (JP) 2017-01-11 EP disclosed
US-9120948-B2 Process for producing block polymer, coated pigment and aqueous pigment dispersion DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2015-09-01 US disclosed
US-20130196064-A1 PROCESS FOR PRODUCING BLOCK POLYMER, COATED PIGMENT AND AQUEOUS PIGMENT DISPERSION KYOTO UNIVERSITY (JP) 2013-08-01 US disclosed
EP-2502940-A1 RESIN PARTICLES AND PROCESS FOR PRODUCTION THEREOF Soken Chemical & Engineering Co., Ltd. (JP) 2012-09-26 EP disclosed
US-20120238705-A1 Resin Particles and Process for Producing the Same SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) 2012-09-20 US disclosed
US-20110223529-A1 AQUEOUS PIGMENT DISPERSION AND APPLICATIONS THEREOF DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2011-09-15 US disclosed
WO-2007067407-A2 A TRANSPARENT ELECTRODE FOR ORGANIC ELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2007-06-14 WO disclosed
US-4696988-A Process for preparation of reactive polymers and polymers prepared by said process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230135119-A1 METHODS OF USING PROTEIN PALMITOYLATIONS INHIBITORS PPT1, SPTLC2, SPTLC1 TAAR1 4441/4885HTR2A 4028/4885DPP4 561/4885
US-10858491-B2 Porous particle made of organic polymer, method for producing porous particle made of organic polymer, and block copolymer SPOP, NUP205, ATP5PO TAAR1 4133/4885HTR2A 2148/4885DPP4 4451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.