SCHEMBL2846319

SCHEMBL2846319

CC(N)(c1ccccc1P(C1CCCCC1)C1CCCCC1)c1ccccc1P(C1CCCCC1)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
ROCK2 O75116 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16694309 0.79 ALDH1A1 (0.31)
SCHEMBL1315359 0.78 ROCK2 (0.35) LMNAROCK2
SCHEMBL1314189 0.75 ROCK2 (0.33) ROCK2
SCHEMBL8091041 0.74
SCHEMBL17583591 0.74 ROCK2 (0.33) ROCK2
SCHEMBL301552 0.73 NPC1 (0.38) LMNAROCK2
SCHEMBL14905782 0.73 GAA (0.43) ROCK2
SCHEMBL520084 0.72 BCHE (0.37) LMNAROCK2
SCHEMBL2364217 0.72 BCHE (0.30) ROCK2
SCHEMBL3165316 0.72 NPC1 (0.37) LMNAROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US claimed
US-8436111-B2 Nickel catalyst system for the preparation of high CIS polybutadiene BRIDGESTONE CORPORATION (JP) 2013-05-07 US disclosed
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US disclosed