SCHEMBL301552

SCHEMBL301552

Cc1ccccc1P(C1CCCCC1)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SIGMAR1 Q99720 3/20 0.36
P2RX7 Q99572 3/20 0.36
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
TSHR P16473 2/20 0.35
ACHE P22303 1/20 0.35
LMNA P02545 1/20 0.34
ROCK2 O75116 1/20 0.34
ALOX12 P18054 1/20 0.33
EPHX1 P07099 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3165316 0.98 NPC1 (0.37) NPC1RAB9ASIGMAR1P2RX7GRIN2D
SCHEMBL3185842 0.98 TSHR (0.36) NPC1RAB9ASIGMAR1P2RX7GRIN2D
SCHEMBL3170606 0.96 TSHR (0.35) NPC1RAB9ASIGMAR1P2RX7GRIN2D
SCHEMBL15659453 0.90 ACHE (0.39) NPC1RAB9ATSHRACHELMNA
SCHEMBL29391022 0.85 S1PR1 (0.36) NPC1RAB9ASIGMAR1P2RX7GRIN2D
SCHEMBL197441 0.85 S1PR1 (0.36) NPC1RAB9ASIGMAR1P2RX7GRIN2D
SCHEMBL29350531 0.85 S1PR1 (0.36) NPC1RAB9ASIGMAR1P2RX7GRIN2D
SCHEMBL1315359 0.85 ROCK2 (0.35) TSHRACHELMNAROCK2ALOX12
SCHEMBL15660440 0.85 GAA (0.40) NPC1RAB9ASIGMAR1P2RX7TSHR
SCHEMBL205843 0.85 ROCK2 (0.38) NPC1RAB9ASIGMAR1P2RX7GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118388585-A Preparation method of amide and ester compounds based on visible light catalysis 泰山学院 2024-07-26 CN claimed
WO-2019016115-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED ARYL KETONES BASF Agro B.V. (NL) 2019-01-24 WO claimed
US-6686495-B2 IN PRESENCE OF PALLADIUM CATALYST; USEFUL IN PRODUCING CHEMICAL INTERMEDIATES FOR PHARMACEUTICALS, OPTICAL BRIGHTENING AGENTS AND AGROCHEMICALS OMG AG & CO KG (DE) 2004-02-03 US claimed
US-20020107426-A1 Process for the preparation of mono-, bi- or poly- functional biaryls UMICORE AG & CO. KG (DE) 2002-08-08 US claimed
EP-1199292-A1 Process for the production of mono-, bi- or polyfunctional biaryls OMG AG & Co. KG (DE) 2002-04-24 EP claimed
EP-3892611-B1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN IND LTD (JP) 2026-01-28 EP disclosed
US-20250214936-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-07-03 US disclosed
US-12281075-B2 Method for producing fluorovinyl amide compound DAIKIN INDUSTRIES, LTD. (JP) 2025-04-22 US disclosed
WO-2025016436-A1 PREPARATION METHOD FOR KRAS INHIBITOR, INTERMEDIATE THEREOF AND PREPARATION METHOD FOR INTERMEDIATE THEREOF 上海济煜医药科技有限公司 2025-01-23 WO disclosed
CN-118388585-A Preparation method of amide and ester compounds based on visible light catalysis 泰山学院 2024-07-26 CN disclosed
US-11932596-B2 Fluorovinyl ether compound DAIKIN INDUSTRIES, LTD. (JP) 2024-03-19 US disclosed
EP-3643694-B1 METHOD FOR PRODUCING BUTADIENE COMPOUND DAIKIN IND LTD (JP) 2023-11-15 EP disclosed
US-20040082814-A1 Process for producing retinol and intermediate compounds for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2004-04-29 US disclosed
US-6686495-B2 IN PRESENCE OF PALLADIUM CATALYST; USEFUL IN PRODUCING CHEMICAL INTERMEDIATES FOR PHARMACEUTICALS, OPTICAL BRIGHTENING AGENTS AND AGROCHEMICALS OMG AG & CO KG (DE) 2004-02-03 US disclosed
US-6660888-B2 A disulfone compound of given formula SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-09 US disclosed
US-20020107426-A1 Process for the preparation of mono-, bi- or poly- functional biaryls UMICORE AG & CO. KG (DE) 2002-08-08 US disclosed
CN-1356317-A Process for producing retinol and intermediate compound for producing retinol SUMITOMO CHEMICAL CO (JP) 2002-07-03 CN disclosed
US-20020058844-A1 Process for producing retinol and intermediate compounds for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-16 US disclosed
EP-1199303-A1 Process for producing retinol and intermediate compounds for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-24 EP disclosed
EP-1199292-A1 Process for the production of mono-, bi- or polyfunctional biaryls OMG AG & Co. KG (DE) 2002-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11932596-B2 Fluorovinyl ether compound RB1, AFF1, AFF2 NPC1 3797/4885RAB9A 649/4885SIGMAR1 4288/4885
US-20040082814-A1 Process for producing retinol and intermediate compounds for producing the same ADH4, ADH1B, ADH7 NPC1 2226/4885RAB9A 1374/4885SIGMAR1 1836/4885
US-12281075-B2 Method for producing fluorovinyl amide compound RB1, KRAS, NRAS NPC1 3488/4885RAB9A 318/4885SIGMAR1 4094/4885
US-20250214936-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND RB1, KRAS, NRAS NPC1 3488/4885RAB9A 318/4885SIGMAR1 4094/4885
US-20020058844-A1 Process for producing retinol and intermediate compounds for producing the same ADH4, ADH1B, ADH7 NPC1 2226/4885RAB9A 1374/4885SIGMAR1 1836/4885
US-20020107426-A1 Process for the preparation of mono-, bi- or poly- functional biaryls CYP4F3, CYP4F2, CYP2F1 NPC1 2800/4885RAB9A 2663/4885SIGMAR1 1502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.