Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27830131 | 0.85 | LMNA (0.43) | — | |
| Hydrochlorthiazide SCHEMBL352730 | 0.84 | — | — | |
| Hydrochlorthiazide SCHEMBL677154 | 0.82 | — | — | |
| Hydrochlorthiazide SCHEMBL28250666 | 0.80 | — | — | |
| Hydrochlorthiazide SCHEMBL2496915 | 0.80 | — | — | |
| Hydrochlorthiazide SCHEMBL29079282 | 0.80 | — | — | |
| Hydrochlorthiazide SCHEMBL4226436 | 0.80 | — | — | |
| Hydrochlorthiazide SCHEMBL17803385 | 0.79 | — | — | |
| Acrylic Acid SCHEMBL28885339 | 0.77 | LMNA (0.36) | — | |
| Hydrochlorthiazide SCHEMBL1422022 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777604-B | Synthesis method of 2-aminothiazole pyrimidine serving as CDK2 inhibitor | 常州大学 | 2021-12-21 | — | — | CN | claimed |
| CN-111777604-A | Synthesis method of 2-aminothiazole pyrimidine serving as CDK2 inhibitor | 常州大学 | 2020-10-16 | — | — | CN | claimed |
| CN-111777604-B | Synthesis method of 2-aminothiazole pyrimidine serving as CDK2 inhibitor | 常州大学 | 2021-12-21 | — | — | CN | disclosed |
| CN-111777604-A | Synthesis method of 2-aminothiazole pyrimidine serving as CDK2 inhibitor | 常州大学 | 2020-10-16 | — | — | CN | disclosed |