SCHEMBL28463293

SCHEMBL28463293

C=Cc1nc2ccccc2n1OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.42
SMN1; SMN2 Q16637 12/20 0.42
ALDH1A1 P00352 11/20 0.42
RAB9A P51151 10/20 0.42
NPC1 O15118 9/20 0.42
MAPT P10636 5/20 0.42
PKM P14618 5/20 0.42
LMNA P02545 3/20 0.42
CDK5 Q00535 1/20 0.42
PAX8 Q06710 1/20 0.42
CDK5R1 Q15078 1/20 0.42
RCE1 Q9Y256 1/20 0.42
L3MBTL1 Q9Y468 6/20 0.41
KMT2A Q03164 1/20 0.41
GLA P06280 5/20 0.40
GAA P10253 5/20 0.40
HPGD P15428 7/20 0.40
TP53 P04637 5/20 0.40
HSD17B10 Q99714 2/20 0.40
TSHR P16473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9675063 0.83 VDR (0.48) KDM4ESMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL1656174 0.77 KDM4E (0.42) KDM4ESMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL11699121 0.77 KDM4E (0.64) KDM4ESMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL3969616 0.74 HTT (0.52) KDM4ESMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL30897342 0.73 RAB9A (0.69) KDM4ESMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL3974206 0.73 SMN1; SMN2 (0.44) KDM4ESMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL16752435 0.73 SMN1; SMN2 (0.44) KDM4ESMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL11669582 0.73 NOS2 (0.55) KDM4ESMN1; SMN2RAB9ANPC1MAPT
SCHEMBL28856696 0.73 SMN1; SMN2 (0.44) KDM4ESMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL3967680 0.73 SMN1; SMN2 (0.60) KDM4ESMN1; SMN2RAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108950645-B Aluminum and aluminum alloy anodic oxidation nickel-free sealing agent 上海铝通化学科技有限公司 2020-10-23 CN disclosed