Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467009 | 0.80 | MAP2K1 (0.43) | MAP2K1CAMKK2 | |
| SCHEMBL22978453 | 0.77 | NPC1 (0.35) | PARP1PARP2PARP3 | |
| SCHEMBL28466209 | 0.75 | CAMKK2 (0.37) | MAP2K1PARP1CAMKK2 | |
| SCHEMBL28462467 | 0.72 | MAP2K1 (0.47) | MAP2K1CAMKK2 | |
| SCHEMBL23630658 | 0.66 | NNMT (0.41) | — | |
| SCHEMBL27927500 | 0.66 | POLB (0.47) | MAP2K1PARP1CAMKK2 | |
| SCHEMBL25167319 | 0.65 | CA12 (0.50) | — | |
| SCHEMBL28355063 | 0.65 | PIK3CA (0.35) | — | |
| SCHEMBL27710771 | 0.64 | NNMT (0.39) | — | |
| SCHEMBL29732854 | 0.64 | CAMKK2 (0.46) | MAP2K1PARP1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461849-B | CSF1R inhibitor and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-110461849-A | A kind of CSF1R inhibitor and its preparation method and application | ABBISKO THERAPEUTICS CO LTD | 2019-11-15 | — | — | CN | disclosed |