Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472389 | 0.94 | TP53 (0.54) | HTTKDM4ESMN1; SMN2PLK1L3MBTL1 | |
| SCHEMBL28459280 | 0.91 | TP53 (0.59) | HTTKDM4ESMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL28467015 | 0.87 | KMT2A (0.56) | KDM4EPLK1ACACBMAPTMEN1 | |
| SCHEMBL28459281 | 0.82 | MEN1 (0.67) | HTTKDM4ESMN1; SMN2PLK1L3MBTL1 | |
| SCHEMBL7733569 | 0.78 | MAPT (0.59) | SMN1; SMN2PLK1MAPTALOX15 | |
| SCHEMBL9781935 | 0.78 | L3MBTL1 (0.56) | HTTKDM4ESMN1; SMN2PLK1L3MBTL1 | |
| SCHEMBL1442973 | 0.78 | L3MBTL1 (0.78) | HTTKDM4ESMN1; SMN2PLK1L3MBTL1 | |
| SCHEMBL28861868 | 0.77 | ELANE (0.53) | HTTSMN1; SMN2L3MBTL1MAPTMEN1 | |
| SCHEMBL28462599 | 0.77 | MEN1 (0.60) | KDM4ESMN1; SMN2PLK1MAPTCYP2C19 | |
| SCHEMBL7632695 | 0.76 | L3MBTL1 (0.74) | HTTKDM4ESMN1; SMN2PLK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |