Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196711 | 0.95 | KCNA3 (0.34) | KCNA3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27567586 | 0.93 | KCNA3 (0.35) | KCNA3 | |
| SCHEMBL4630510 | 0.88 | KCNA3 (0.32) | KCNA3 | |
| SCHEMBL9113345 | 0.83 | LTA4H (0.34) | MAPTKCNA3MEN1KMT2AHDAC6 | |
| SCHEMBL9668765 | 0.83 | LTA4H (0.41) | MAPTMEN1KMT2AHDAC6 | |
| SCHEMBL7861358 | 0.83 | LTA4H (0.41) | MAPTMEN1KMT2AHDAC6 | |
| SCHEMBL8196472 | 0.83 | NPC1 (0.47) | SMN1; SMN2NPC1MAPTRAB9AKMT2A | |
| SCHEMBL3140129 | 0.82 | NPC1 (0.33) | SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL7274140 | 0.82 | LTA4H (0.40) | SMN1; SMN2MAPTMEN1KMT2AHDAC6 | |
| SCHEMBL991125 | 0.81 | LTA4H (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111704543-A | Process and intermediates for preparing alpha, omega-dicarboxylic acid terminated dialkyl ethers | 燿石治疗公司 | 2020-09-25 | — | — | CN | disclosed |