Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861358 | 0.93 | LTA4H (0.41) | LTA4HALDH1A1APAF1RAD52NPSR1 | |
| SCHEMBL9668765 | 0.93 | LTA4H (0.41) | LTA4HALDH1A1APAF1RAD52NPSR1 | |
| SCHEMBL7274140 | 0.92 | LTA4H (0.40) | LTA4HALDH1A1APAF1RAD52NPSR1 | |
| SCHEMBL991125 | 0.92 | LTA4H (0.42) | LTA4HALDH1A1APAF1RAD52NPSR1 | |
| SCHEMBL7281298 | 0.90 | L3MBTL1 (0.37) | LTA4HALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL10710501 | 0.88 | LTA4H (0.41) | LTA4HALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL4943659 | 0.88 | LTA4H (0.44) | LTA4HALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL5144146 | 0.88 | LTA4H (0.44) | LTA4HALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL2871187 | 0.88 | LTA4H (0.44) | LTA4HALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL5495328 | 0.88 | LTA4H (0.44) | LTA4HALDH1A1TSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |