Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571722 | 0.98 | LMNA (0.47) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL31571723 | 0.98 | LMNA (0.47) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL31571724 | 0.98 | LMNA (0.47) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL28544833 | 0.98 | LMNA (0.47) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL25748480 | 0.90 | LMNA (0.45) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL29086906 | 0.84 | LMNA (0.39) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL9949410 | 0.82 | ALDH1A1 (0.38) | LMNAMAPTDNM1ALDH1A1HSD17B10 | |
| SCHEMBL31532959 | 0.81 | LMNA (0.48) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL11481045 | 0.81 | LMNA (0.48) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL126362 | 0.81 | LMNA (0.48) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793352-A | Waterborne polyurethane powder adhesive, elastic material and preparation method thereof | 惠州大亚湾达志精细化工有限公司 | 2020-10-20 | — | — | CN | claimed |