Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15257937 | 0.75 | JAK3 (0.33) | — | |
| SCHEMBL23508934 | 0.75 | HTT (0.33) | TTRALB | |
| SCHEMBL15257962 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL1336348 | 0.75 | ALOX5AP (0.31) | — | |
| SCHEMBL12466516 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL12466671 | 0.75 | CSNK1A1 (0.37) | — | |
| SCHEMBL28648721 | 0.75 | HTT (0.33) | — | |
| SCHEMBL28691950 | 0.68 | GABRG2 (0.35) | — | |
| SCHEMBL28469042 | 0.67 | — | — | |
| SCHEMBL25275854 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113106130-B | Application of nitrile hydratase derived from staphylococcus aggregatus in preparation of amide pyrazine compounds | 核芯生物医药科技(杭州)有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-113106130-A | Application of nitrile hydratase derived from staphylococcus aggregatus in preparation of amide pyrazine compounds | 浙江恒康药业股份有限公司 | 2021-07-13 | — | — | CN | claimed |
| CN-113025671-A | Application of nitrile hydratase derived from sinorhizobium meliloti in preparation of amide pyrazine compounds | 浙江恒康药业股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-111662938-A | Application of nitrile hydratase in catalyzing hydration reaction of cyanopyrazine compound to generate amide pyrazine compound | 浙江恒康药业股份有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-113106130-B | Application of nitrile hydratase derived from staphylococcus aggregatus in preparation of amide pyrazine compounds | 核芯生物医药科技(杭州)有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-113025671-B | Application of nitrile hydratase derived from sinorhizobium meliloti in preparation of amide pyrazine compounds | 浙江恒康药业股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-113106130-A | Application of nitrile hydratase derived from staphylococcus aggregatus in preparation of amide pyrazine compounds | 浙江恒康药业股份有限公司 | 2021-07-13 | — | — | CN | disclosed |
| CN-113025671-A | Application of nitrile hydratase derived from sinorhizobium meliloti in preparation of amide pyrazine compounds | 浙江恒康药业股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-111662938-B | Application of nitrile hydratase in catalyzing hydration reaction of cyanopyrazine compound to generate amide pyrazine compound | 浙江恒康药业股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-111662938-A | Application of nitrile hydratase in catalyzing hydration reaction of cyanopyrazine compound to generate amide pyrazine compound | 浙江恒康药业股份有限公司 | 2020-09-15 | — | — | CN | disclosed |