Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794034 | 0.83 | ALOX5AP (0.33) | ALOX5APFEN1 | |
| SCHEMBL29093198 | 0.83 | ALOX5AP (0.32) | ALOX5APFEN1 | |
| SCHEMBL28456157 | 0.82 | CTSK (0.39) | ALOX5APFEN1 | |
| SCHEMBL29379576 | 0.78 | CYP11B2 (0.33) | — | |
| SCHEMBL1338236 | 0.78 | CYP11B2 (0.33) | — | |
| SCHEMBL23508934 | 0.75 | HTT (0.33) | — | |
| SCHEMBL6376942 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL15257937 | 0.75 | JAK3 (0.33) | — | |
| SCHEMBL28464487 | 0.75 | TTR (0.30) | — | |
| SCHEMBL6375598 | 0.75 | ALOX5AP (0.42) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230098076-A1 | A PROCESS FOR PREPARATION OF 3,6-DICHLOROCYANO PYRAZINE, 3,6-DIOXOPIPERAZINE DERIVATIVES AND PRODUCTION OF FAVIPIRAVIR THEREOF | COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN (IN) | 2023-03-30 | — | — | US | claimed |
| CN-113106130-B | Application of nitrile hydratase derived from staphylococcus aggregatus in preparation of amide pyrazine compounds | 核芯生物医药科技(杭州)有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-113025671-B | Application of nitrile hydratase derived from sinorhizobium meliloti in preparation of amide pyrazine compounds | 浙江恒康药业股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-112552245-B | Synthesis method of Favipiravir | 苏州正济药业有限公司 | 2022-08-02 | — | — | CN | claimed |
| WO-2022009036-A1 | SYNTHESIS OF FAVIPIRAVIR | OPTIMUS DRUGS (P) LTD (IN) | 2022-01-13 | — | — | WO | claimed |
| CN-215277128-U | Automatic feeding device for synthesizing 6-fluoro-3-hydroxy-2-cyanopyrazine | 江西美晶科技有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-215196902-U | Efficient hydrolysis reaction kettle for 6-fluoro-3-hydroxy-2-cyanopyrazine | 江西美晶科技有限公司 | 2021-12-17 | — | — | CN | claimed |
| WO-2021250705-A1 | A PROCESS FOR PREPARATION OF 3,6-DICHLOROCYANO PYRAZINE, 3,6-DIOXOPIPERAZINE DERIVATIVES AND PRODUCTION OF FAVIPIRAVIR THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860)) (IN) | 2021-12-16 | — | — | WO | claimed |
| WO-2021240295-A1 | PROCESS FOR PREPARATION OF FAVIPIRAVIR | GLENMARK LIFE SCIENCES LIMITED (IN) | 2021-12-02 | — | — | WO | claimed |
| CN-113252800-A | HPLC (high performance liquid chromatography) detection method for Pilarvir and related substances thereof and application of method | 北京四环制药有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-113025671-A | Application of nitrile hydratase derived from sinorhizobium meliloti in preparation of amide pyrazine compounds | 浙江恒康药业股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-111662938-B | Application of nitrile hydratase in catalyzing hydration reaction of cyanopyrazine compound to generate amide pyrazine compound | 浙江恒康药业股份有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-112645889-A | Refining method of Favipiravir | 杭州煌森生物科技有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-112552245-A | Synthesis method of Favipiravir | 苏州正济药业有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-111675663-A | Preparation method of Favipiravir | 杭州煌森生物科技有限公司 | 2020-09-18 | — | — | CN | claimed |
| CN-111662938-A | Application of nitrile hydratase in catalyzing hydration reaction of cyanopyrazine compound to generate amide pyrazine compound | 浙江恒康药业股份有限公司 | 2020-09-15 | — | — | CN | claimed |
| EP-2192117-B1 | ORGANIC AMINE SALT OF 6-FLUORO-3-HYDROXY-2-PYRAZINECARBONITRILE AND METHOD FOR PRODUCING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2014-06-04 | — | — | EP | claimed |
| US-8168789-B2 | Organic amine salt of 6-fluoro-3-hydroxy-2-pyrazinecarbonitrile and method for producing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | claimed |
| US-20100286394-A1 | ORGANIC AMINE SALT OF 6-FLUORO-3-HYDROXY-2-PYRAZINECARBONITRILE AND METHOD FOR PRODUCING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-11-11 | — | — | US | claimed |
| EP-2192117-A1 | ORGANIC AMINE SALT OF 6-FLUORO-3-HYDROXY-2-PYRAZINECARBONITRILE AND METHOD FOR PRODUCING THE SAME | Toyama Chemical Co., Ltd. (JP) | 2010-06-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230098076-A1 | A PROCESS FOR PREPARATION OF 3,6-DICHLOROCYANO PYRAZINE, 3,6-DIOXOPIPERAZINE DERIVATIVES AND PRODUCTION OF FAVIPIRAVIR THEREOF | CBR3, CYP4F3, CYP3A5 | ALOX5AP 615/4885FEN1 2774/4885 |
| US-20100286394-A1 | ORGANIC AMINE SALT OF 6-FLUORO-3-HYDROXY-2-PYRAZINECARBONITRILE AND METHOD FOR PRODUCING THE SAME | AOC2, HTR2A, HTR2C | ALOX5AP 1710/4885FEN1 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.