Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.73 |
| ▸ | MIF | P14174 | 4/20 | 0.73 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | GRM5 | P41594 | 2/20 | 0.56 |
| ▸ | OGT | O15294 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.45 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27166024 | 0.91 | FLT3 (0.64) | FLT3MIFGSK3BGRM5OGT | |
| SCHEMBL6953018 | 0.90 | FLT3 (0.77) | FLT3MIFGSK3BGRM5PTGS2 | |
| SCHEMBL26628293 | 0.90 | MIF (0.91) | FLT3MIFGSK3BGRM5OGT | |
| SCHEMBL26628323 | 0.90 | FLT3 (0.68) | FLT3MIFGSK3BGRM5OGT | |
| SCHEMBL17980671 | 0.84 | MIF (1.00) | FLT3MIFGSK3BGRM5HSD17B1 | |
| SCHEMBL1674373 | 0.84 | FLT3 (0.73) | FLT3MIFGSK3BGRM5PTGS2 | |
| SCHEMBL29158520 | 0.84 | FLT3 (1.00) | FLT3MIFGSK3BGRM5PTGS2 | |
| SCHEMBL26628312 | 0.83 | PTGS2 (0.67) | FLT3MIFGSK3BOGTPTGS2 | |
| SCHEMBL28468629 | 0.81 | FLT3 (0.56) | FLT3MIFGSK3BGRM5STIM1 | |
| SCHEMBL12595574 | 0.81 | FLT3 (0.56) | FLT3MIFGSK3BGRM5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808922-A | Bacterial ribosome inhibitor screening method and inhibitor thereof | 四川大学 | 2020-10-23 | — | — | CN | claimed |
| CN-111808922-A | Bacterial ribosome inhibitor screening method and inhibitor thereof | 四川大学 | 2020-10-23 | — | — | CN | disclosed |