SCHEMBL6953018

SCHEMBL6953018

c1ccc(-n2cc(-c3ccccn3)nn2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 4/20 0.77
MIF P14174 3/20 0.77
GRM5 P41594 1/20 0.65
GSK3B P49841 1/20 0.64
KDM4E B2RXH2 2/20 0.50
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
CCR1 P32246 1/20 0.50
CCR5 P51681 1/20 0.50
CCR8 P51685 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
NPC1 O15118 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28464554 0.90 FLT3 (0.73) FLT3MIFGRM5GSK3BCA12
SCHEMBL29158520 0.87 FLT3 (1.00) FLT3MIFGRM5GSK3BKDM4E
SCHEMBL17980671 0.87 MIF (1.00) FLT3MIFGRM5GSK3BNPC1
SCHEMBL1674373 0.87 FLT3 (0.73) FLT3MIFGRM5GSK3BKDM4E
SCHEMBL31373412 0.84 FLT3 (0.66) FLT3MIFGRM5GSK3BKDM4E
SCHEMBL27166024 0.83 FLT3 (0.64) FLT3MIFGRM5GSK3BCA12
SCHEMBL5202573 0.83 FLT3 (0.72) FLT3MIFGRM5GSK3BKDM4E
SCHEMBL30291136 0.83 FLT3 (0.68) FLT3MIFGRM5GSK3BKDM4E
SCHEMBL26628323 0.83 FLT3 (0.68) FLT3MIFGRM5GSK3BKDM4E
SCHEMBL2192371 0.83 FLT3 (0.72) FLT3MIFGRM5GSK3BMETAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163088-A1 HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF DEBRECENI EGYETEM (HU) 2025-05-22 US disclosed
EP-4463230-A1 HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF Debreceni Egyetem (HU) 2024-11-20 EP disclosed
WO-2023041947-A1 HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF DEBRECENI EGYETEM (HU) 2023-03-23 WO disclosed
EP-3169674-B1 ARYL-TRIAZOLYL-PYRIDINES AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2021-01-20 EP disclosed
US-10208015-B2 Aryl-triazolyl pyridines as pest control agents BAYER ANIMAL HEALTH GMBH (DE) 2019-02-19 US disclosed
EP-2991997-B1 TRANSITION METAL COMPLEXES WITH CARBENE LIGANDS AND THE USE THEREOF IN OLEDS UDC IRELAND LTD (IE) 2018-02-21 EP disclosed
US-20170144988-A1 ARYL-TRIAZOLYL PYRIDINES AS PEST CONTROL AGENTS ELANCO ANIMAL HEALTH GMBH (DE) 2017-05-25 US disclosed
EP-3169674-A1 ARYL-TRIAZOLYL PYRIDINES AS PEST CONTROL AGENTS Bayer Animal Health GmbH (DE) 2017-05-24 EP disclosed
US-20160072081-A1 Transition metal complexes with carbene ligands and the use thereof in OLEDs BASF SE (DE) 2016-03-10 US disclosed
US-20160072081-A1 Transition metal complexes with carbene ligands and the use thereof in OLEDs BASF SE (DE) 2016-03-10 US disclosed
WO-2016008830-A1 ARYL-TRIAZOLYL PYRIDINES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-21 WO disclosed
WO-2014177518-A1 TRANSITION METAL COMPLEXES WITH CARBENE LIGANDS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2014-11-06 WO disclosed
EP-0559363-B1 3-Phenyl-5-pyridyl triazoles and their use as insecticides KUMIAI CHEMICAL INDUSTRY CO (JP) 2003-10-29 EP disclosed
EP-0559363-A1 3-Phenyl-5-pyridyl triazoles and their use as insecticides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163088-A1 HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF SLC39A3, CUTA, SLC30A6 FLT3 717/4885MIF 52/4885GRM5 3296/4885
US-20170144988-A1 ARYL-TRIAZOLYL PYRIDINES AS PEST CONTROL AGENTS PTMS, TYR, PDXK FLT3 141/4885MIF 2961/4885GRM5 1090/4885
US-20160072081-A1 Transition metal complexes with carbene ligands and the use thereof in OLEDs OCIAD1, OCIAD2, TRPM6 FLT3 3780/4885MIF 303/4885GRM5 389/4885
US-10208015-B2 Aryl-triazolyl pyridines as pest control agents PTMS, TYR, PDXK FLT3 141/4885MIF 2961/4885GRM5 1090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.