SCHEMBL28464622

SCHEMBL28464622

COc1cccc([S+]([O-])Cc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
SIGMAR1 Q99720 1/20 0.45
TAAR1 Q96RJ0 3/20 0.44
IDO1 P14902 2/20 0.44
AGXT P21549 2/20 0.44
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CASR P41180 1/20 0.42
TAS2R14 Q9NYV8 1/20 0.42
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
CALM1 P0DP23 1/20 0.41
CAMKK2 Q96RR4 1/20 0.41
USP2 O75604 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28864900 0.82 CYP1A2 (0.46) MAOBSIGMAR1TAAR1IDO1AGXT
SCHEMBL29285349 0.81 LTA4H (0.53) SIGMAR1IDO1AGXTUSP2CA4
SCHEMBL11986334 0.78 ACHE (0.42) MAOBTAAR1IDO1AGXTCHRM2
SCHEMBL7329519 0.78 ACHE (0.42) MAOBTAAR1IDO1AGXTCHRM2
SCHEMBL21177496 0.78 MAOB (0.41) MAOBSIGMAR1TAAR1IDO1AGXT
SCHEMBL21182305 0.78 MAOB (0.41) MAOBSIGMAR1TAAR1IDO1AGXT
SCHEMBL30047680 0.76 CALM1 (0.39) MAOBTAAR1IDO1POLBCALM1
SCHEMBL30047777 0.76 CALM1 (0.39) MAOBTAAR1IDO1POLBCALM1
SCHEMBL28906945 0.76 CALM1 (0.39) MAOBTAAR1IDO1POLBCALM1
SCHEMBL779948 0.76 CALM1 (0.39) MAOBTAAR1IDO1POLBCALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109485587-B Method for preparing sulfoxide compound by one-step reaction of benzyl chloride compound and thiophenol under metal-free condition 陕西师范大学 2020-10-16 CN disclosed