Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 9/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16815333 | 0.81 | ACHE (0.50) | SORDACHE | |
| SCHEMBL28059125 | 0.81 | ACHE (0.46) | SORDACHE | |
| SCHEMBL16815392 | 0.80 | PIK3CA (0.51) | SORDACHEPIK3CA | |
| SCHEMBL20745663 | 0.79 | SORD (0.41) | SORDNR1H2AOC3PANK3PIK3CA | |
| SCHEMBL20745038 | 0.78 | PIK3CA (0.50) | SORDACHEPIK3CA | |
| SCHEMBL20746289 | 0.78 | PIK3CA (0.50) | SORDACHEPIK3CA | |
| SCHEMBL20745280 | 0.78 | ACHE (0.50) | SORDNR1H2AOC3ACHEPIK3CA | |
| SCHEMBL20745655 | 0.77 | SORD (0.40) | SORDNR1H2AOC3PANK3ACHE | |
| SCHEMBL20746494 | 0.76 | TRPV3 (0.42) | SORDNR1H2AOC3PANK3 | |
| SCHEMBL22262291 | 0.76 | ACHE (0.52) | SORDNR1H2AOC3PANK3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111818916-A | Macrocyclic MCL-1 inhibitors and methods of use | 艾伯维公司 | 2020-10-23 | — | — | CN | disclosed |