Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 5/20 | 0.67 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | CFTR | P13569 | 9/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171356 | 0.90 | BAZ2B (0.82) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL602333 | 0.86 | LMNA (0.67) | BAZ2BKDRCFTRADRA2AADRA2B | |
| SCHEMBL21114768 | 0.85 | BAZ2B (0.61) | BAZ2BKDRCFTRADRA2AADRA2B | |
| SCHEMBL30506408 | 0.85 | BAZ2B (0.61) | BAZ2BKDRCFTRADRA2AADRA2B | |
| SCHEMBL18345747 | 0.84 | BAZ2B (0.65) | BAZ2BCFTRUSP2LMNAMAPT | |
| SCHEMBL3476781 | 0.81 | BAZ2B (0.64) | BAZ2BCFTRUSP2LMNAMAPT | |
| SCHEMBL28661381 | 0.81 | BAZ2B (0.64) | BAZ2BCFTRALOX15HSD17B10LMNA | |
| SCHEMBL5372790 | 0.81 | BAZ2B (0.67) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL18346075 | 0.78 | CFTR (0.52) | BAZ2BCFTRLMNAMAPTPABPC1 | |
| Fumaric Acid SCHEMBL25201865 | 0.78 | HTR7 (0.53) | BAZ2BKDRCFTRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757882-A | 1,3,4, 5-tetrahydro-2H-pyrido [4,3-b ] indole derivatives for the treatment, alleviation or prevention of disorders associated with Tau aggregates such as alzheimer's disease | AC免疫有限公司 | 2020-10-09 | — | — | CN | disclosed |