Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | THRA | P10827 | 7/20 | 0.56 |
| ▸ | THRB | P10828 | 7/20 | 0.56 |
| ▸ | RARB | P10826 | 4/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28460406 | 0.95 | THRA (0.63) | PLK1THRATHRBRARBMEN1 | |
| SCHEMBL28466726 | 0.90 | PLK1 (0.54) | PLK1THRATHRBTRPV1KMT2A | |
| SCHEMBL28470841 | 0.83 | ALDH1A1 (0.52) | PLK1THRATHRBMEN1KMT2A | |
| SCHEMBL28459349 | 0.82 | TRPV1 (0.63) | PLK1THRATHRBRARBTRPV1 | |
| SCHEMBL18977659 | 0.80 | PLK1 (0.49) | PLK1THRATHRBRARBTRPV1 | |
| SCHEMBL19449792 | 0.80 | EPHX2 (0.41) | PLK1THRATHRBKMT2APOLB | |
| SCHEMBL28472389 | 0.79 | TP53 (0.54) | PLK1RARBKMT2A | |
| SCHEMBL5382633 | 0.78 | THRA (0.61) | PLK1THRATHRBRARBTRPV1 | |
| SCHEMBL19449796 | 0.78 | KMT2A (0.40) | PLK1THRATHRBKMT2APOLB | |
| SCHEMBL19435750 | 0.78 | CA1 (0.48) | PLK1THRATHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |