Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.63 |
| ▸ | PLK1 | P53350 | 5/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28465310 | 0.96 | TRPV1 (0.58) | TRPV1PLK1HDAC8RARBPLK3 | |
| SCHEMBL28459351 | 0.91 | PLK1 (0.61) | TRPV1PLK1HDAC8TMEM97SIGMAR1 | |
| SCHEMBL28469389 | 0.85 | PLK1 (0.59) | TRPV1PLK1HDAC1NPC1POLB | |
| SCHEMBL24534682 | 0.82 | PLK1 (0.67) | TRPV1PLK1RARBTHRATHRB | |
| SCHEMBL28466232 | 0.82 | PLK1 (0.57) | TRPV1PLK1RARBTHRATHRB | |
| SCHEMBL28462599 | 0.82 | MEN1 (0.60) | PLK1NPC1POLBRAB9AKMT2A | |
| SCHEMBL28463607 | 0.80 | NR1H4 (0.59) | PLK1RARBNPC1POLBRAB9A | |
| SCHEMBL6551314 | 0.79 | ALDH1A1 (0.55) | HDAC8HDAC1NPC1RAB9AKMT2A | |
| SCHEMBL7638853 | 0.79 | TRPV1 (0.65) | TRPV1PLK1RARBTHRATHRB | |
| SCHEMBL22505170 | 0.78 | PLK1 (0.65) | TRPV1PLK1RARBTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |