Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616976 | 0.89 | CNR2 (0.50) | FAAHCES1MAPTBLMKMT2A | |
| SCHEMBL28404561 | 0.88 | FAAH (0.51) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL28988025 | 0.84 | FAAH (0.47) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL15758444 | 0.83 | FAAH (0.54) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL28765511 | 0.82 | LPAR1 (0.44) | FAAHCES1CYP1A2MAPTCYP2C19 | |
| SCHEMBL28516851 | 0.81 | FAAH (0.51) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL109910 | 0.81 | FAAH (0.51) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL5712972 | 0.80 | CA12 (0.41) | FAAHCES1CYP1A2HSD17B10KMT2A | |
| SCHEMBL4617910 | 0.80 | CA12 (0.41) | FAAHCES1CYP1A2HSD17B10KMT2A | |
| SCHEMBL27500926 | 0.80 | CNR2 (0.48) | FAAHCES1CYP1A2MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301965-A | Hair care system, hair care method and use of hair care system | 欧莱雅 | 2021-08-24 | — | — | CN | disclosed |
| CN-107207739-B | Amine-imino diol neutralizing agents for low volatile compound waterborne organic coating compositions and methods of use thereof | 罗地亚经营管理公司 | 2020-09-01 | — | — | CN | disclosed |