Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 5/20 | 0.51 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28836769 | 0.92 | FAAH (0.56) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL28532297 | 0.92 | FAAH (0.43) | FAAHCES1CYP1A2HSD17B10KMT2A | |
| SCHEMBL532715 | 0.89 | FAAH (0.63) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL532713 | 0.89 | FAAH (0.63) | FAAHCES1TERTPTPN1PPARG | |
| Hydrochloric Acid SCHEMBL6565479 | 0.87 | FAAH (0.61) | FAAHCES1TERTPTPN1PPARG | |
| Hydrochloric Acid SCHEMBL6565477 | 0.87 | FAAH (0.61) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL29281613 | 0.87 | FAAH (0.46) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL15758444 | 0.84 | FAAH (0.54) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL27347254 | 0.82 | FAAH (0.58) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL28404561 | 0.82 | FAAH (0.51) | FAAHCES1TERTPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 711 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658508-B2 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2024-06-19 | — | — | EP | claimed |
| EP-2658508-B1 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2021-06-16 | — | — | EP | claimed |
| US-8668746-B2 | Two-part hair colouring composition | KAO GERMANY GMBH (DE) | 2014-03-11 | — | — | US | claimed |
| US-20130305463-A1 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2013-11-21 | — | — | US | claimed |
| EP-2658508-A2 | TWO-PART HAIR COLOURING COMPOSITION | Kao Germany GmbH (DE) | 2013-11-06 | — | — | EP | claimed |
| WO-2012089674-A2 | TWO-PART HAIR COLOURING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2012-07-05 | — | — | WO | claimed |
| EP-2471504-A1 | Two-part hair colouring composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2012-07-04 | — | — | EP | claimed |
| US-20100319719-A1 | COSMETIC COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-12-23 | — | — | US | claimed |
| CN-116322619-B | Hair dyeing composition with improved durability | 花王株式会社 | 2026-05-12 | — | — | CN | disclosed |
| EP-4221667-B1 | BLEACHING AND COLORING COMPOSITION FOR KERATIN FIBERS COMPRISING DIRECT DYES | KAO CORP (JP) | 2024-06-26 | — | — | EP | disclosed |
| US-20240197595-A1 | RESHAPING COMPOSITION FOR KERATIN FIBERS | KAO GERMANY GMBH (DE) | 2024-06-20 | — | — | US | disclosed |
| EP-2658508-B2 | TWO-PART HAIR COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2024-06-19 | — | — | EP | disclosed |
| EP-4221666-B1 | HAIR DYEING COMPOSITION COMPRISING BLUE DYES | KAO CORP (JP) | 2024-06-12 | — | — | EP | disclosed |
| EP-4382172-A1 | COMPOSITION FOR PERMANENT SHAPING OF HUMAN HAIR | Kao Germany GmbH (DE) | 2024-06-12 | — | — | EP | disclosed |
| EP-1454614-A1 | Composition for dyeing human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2004-09-08 | — | — | EP | disclosed |
| EP-1454615-A1 | Composition for dyeing human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2004-09-08 | — | — | EP | disclosed |
| EP-1454613-A1 | Composition for dyeing human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2004-09-08 | — | — | EP | disclosed |
| EP-1428497-A1 | Pre-treatment composition applied before colouring hair with acidic direct dyes | KPSS-Kao Professional Salon Services GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
| EP-1366754-A1 | Composition for the dyeing of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2003-12-03 | — | — | EP | disclosed |
| EP-1366755-A1 | Treatment composition for reducing bleeding of acidic dyes from colored human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2003-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130305463-A1 | TWO-PART HAIR COLOURING COMPOSITION | TYR, CYBA, SMOX | CHRM1 3457/4885FAAH 1815/4885CES1 3502/4885 |
| US-20240197595-A1 | RESHAPING COMPOSITION FOR KERATIN FIBERS | KRT18, CUTA, RER1 | CHRM1 1587/4885FAAH 1396/4885CES1 2087/4885 |
| US-20100319719-A1 | COSMETIC COMPOSITION | SUCLG1, TIPRL, PARG | CHRM1 2542/4885FAAH 1931/4885CES1 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.