Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28463115 | 0.84 | HPGD (0.40) | F2RALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL27874622 | 0.83 | KMT2A (0.42) | ALDH1A1SMN1; SMN2GAAHTTNPC1 | |
| SCHEMBL22981059 | 0.79 | TSHR (0.46) | F2RALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL29524844 | 0.79 | TSHR (0.46) | F2RALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL28370805 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2GAALMNATSHR | |
| SCHEMBL30784110 | 0.75 | NPC1 (0.54) | F2RALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL1928503 | 0.75 | NPC1 (0.54) | F2RALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL28473994 | 0.75 | ALDH1A1 (0.42) | ALDH1A1GAALMNARAB9AADRA1A | |
| SCHEMBL14638890 | 0.75 | CA12 (0.36) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL22980746 | 0.72 | CASP1 (0.40) | F2RALDH1A1GAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | claimed |
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | disclosed |