Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467474 | 0.84 | F2R (0.39) | SMN1; SMN2GAANPC1RAB9AADRA1A | |
| SCHEMBL28319862 | 0.81 | NPC1 (0.44) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL28370805 | 0.80 | SMN1; SMN2 (0.45) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL7640207 | 0.80 | HPGD (0.44) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL28319996 | 0.79 | TSHR (0.50) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL28793889 | 0.77 | HPGD (0.42) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL277670 | 0.75 | NPC1 (0.56) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL991197 | 0.75 | ERCC5 (0.50) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL28470289 | 0.75 | ALDH1A1 (0.41) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL27512567 | 0.74 | ALDH1A1 (0.40) | HPGDSMN1; SMN2GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | claimed |
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | disclosed |