SCHEMBL2846823

SCHEMBL2846823

COC(=O)c1ccc(C(=O)c2ccccc2)o1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
POLB P06746 3/20 0.62
HPGD P15428 3/20 0.62
CYP1A2 P05177 2/20 0.62
GAA P10253 1/20 0.62
CYP2C9 P11712 1/20 0.62
ALDH1A1 P00352 8/20 0.58
MAPT P10636 5/20 0.58
RAB9A P51151 5/20 0.58
LMNA P02545 4/20 0.58
PKM P14618 1/20 0.58
TSHR P16473 1/20 0.57
NPC1 O15118 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
KDM4E B2RXH2 3/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HTT P42858 4/20 0.53
GFER P55789 1/20 0.53
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6281721 0.84 ALDH1A1 (0.62) KMT2AMEN1POLBHPGDALDH1A1
SCHEMBL7392988 0.84 TDP1 (0.58) KMT2AMEN1POLBHPGDCYP1A2
SCHEMBL4898270 0.83 RAB9A (0.59) KMT2AMEN1HPGDALDH1A1MAPT
SCHEMBL2958453 0.83 LMNA (0.64) KMT2AMEN1POLBHPGDCYP1A2
SCHEMBL69791 0.82 HTT (0.69) KMT2AMEN1POLBHPGDCYP1A2
SCHEMBL31571746 0.81 HDAC4 (0.56) KMT2AMEN1HPGDGAACYP2C9
SCHEMBL5371049 0.80 KMT2A (0.49) KMT2AMEN1POLBHPGDCYP1A2
SCHEMBL2852069 0.79 ALDH1A1 (0.56) KMT2AMEN1POLBHPGDALDH1A1
SCHEMBL1660549 0.79 HTT (0.60) KMT2AMEN1POLBHPGDCYP1A2
Ethylene SCHEMBL22615238 0.78 HTT (0.64) KMT2AMEN1POLBHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930868-A Catalyst component containing furoic acid ester compound, preparation method thereof, olefin polymerization catalyst, olefin polymerization method and olefin polymer 中国石油化工股份有限公司 2025-05-06 CN claimed
US-8080567-B2 EP2 receptor agonists ASTERAND UK LIMITED (GB) 2011-12-20 US disclosed
US-8080567-B2 EP2 receptor agonists ASTERAND UK LIMITED (GB) 2011-12-20 US disclosed
US-8080567-B2 EP2 receptor agonists ASTERAND UK LIMITED (GB) 2011-12-20 US disclosed
US-7754751-B2 Preferential inhibition of release of pro-inflammatory cytokines YUNG SHIN PHARMACEUTICAL IND. CO., LTD. (TW) 2010-07-13 US disclosed
US-20100130556-A1 EP2 RECEPTOR AGONISTS ASTERAND UK LIMITED (GB) 2010-05-27 US disclosed
US-20100130556-A1 EP2 RECEPTOR AGONISTS ASTERAND UK LIMITED (GB) 2010-05-27 US disclosed
US-20100130556-A1 EP2 RECEPTOR AGONISTS ASTERAND UK LIMITED (GB) 2010-05-27 US disclosed
EP-1951701-A2 EP2 RECEPTOR AGONISTS ASTERAND UK LIMITED (GB) 2008-08-06 EP disclosed
US-7378532-B2 Fused pyrazolyl compound YUNG SHIN PHARMACEUTICAL IND. CO., LTD. (TW) 2008-05-27 US disclosed
CN-1215060-C Fused pyrazolyl compounds, compositions containing the same, and uses of the compounds YONGXIN MEDICINE INDUSTRY CO L (CN) 2005-08-17 CN disclosed
US-6387942-B2 PYRAZOLYL COMPOUND; ANTICOAGULANTS, ANTIPROLIFERATIVE AGENT YUNG SHIN PHARMACEUTICAL IND. CO. LTD (TW) 2002-05-14 US disclosed
CN-1331076-A Fused pyrazolyl compounds, compositions containing the same, and uses of the compounds YONGXIN MEDICINE INDUSTRY CO L (CN) 2002-01-16 CN disclosed
US-20020004518-A1 Method of treating disorders related to protease-activated receptors-induced cell activation YUNG SHIN PHARMACEUTICAL IND. CO., LTD. (TW) 2002-01-10 US disclosed
EP-1166785-A1 Use of pyrazole derivatives for inhibiting thrombin-induced platelet aggregation Yung Shin Pharmeutical Ind. Co., Ltd. (TW) 2002-01-02 EP disclosed
EP-0667345-B1 1-Benzyl-3-(substituted aryl)-condensed pyrazole derivatives as inhibitors of platelet aggregation YUNG SHIN PHARM IND CO LTD (TW) 1999-09-29 EP disclosed
CN-1039536-C 1, 3-substituted condensed pyrazole compound and application and preparation method thereof YONGXIN PHARMACEUTICAL INDUSTR (CN) 1998-08-19 CN disclosed
US-5574168-A ANTICOAGULANTS YUNG SHIN PHARM. IND. CO., LTD. (TW) 1996-11-12 US disclosed
CN-1112926-A 1, 3-substituted condensed pyrazole compound and application and preparation method thereof YONGXIN PHARMACEUTICAL INDUSTR (CN) 1995-12-06 CN disclosed
EP-0667345-A1 1-Benzyl-3-(substituted aryl)-condensed pyrazole derivatives as inhibitors of platelet aggregation Yung Shin Pharm. Ind. Co. Ltd. (TW) 1995-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130556-A1 EP2 RECEPTOR AGONISTS PTGER3, PTGER2, CNR2 KMT2A 2546/4885MEN1 4201/4885POLB 3892/4885
US-20020004518-A1 Method of treating disorders related to protease-activated receptors-induced cell activation F2R, HPN, F2RL1 KMT2A 3681/4885MEN1 4244/4885POLB 4239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.