Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNNI3K | Q59H18 | 6/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469591 | 0.84 | PRMT5 (0.47) | KAT6AL3MBTL1ALDH1A1GAAPKM | |
| SCHEMBL21353039 | 0.84 | PRMT5 (0.47) | KAT6AL3MBTL1ALDH1A1GAAPKM | |
| SCHEMBL28737824 | 0.83 | PSIP1 (0.41) | POLBKAT6AL3MBTL1ALDH1A1GAA | |
| SCHEMBL28737773 | 0.82 | KAT6A (0.42) | KAT6AKDM4EHTR1DHTR1BTSHR | |
| SCHEMBL28901422 | 0.81 | CA1 (0.47) | KAT6A | |
| SCHEMBL28470108 | 0.80 | CYP1A2 (0.49) | POLBTNNI3KKAT6AL3MBTL1ALDH1A1 | |
| SCHEMBL28470107 | 0.80 | CYP1A2 (0.49) | POLBTNNI3KKAT6AL3MBTL1ALDH1A1 | |
| SCHEMBL14601549 | 0.79 | KAT6A (0.52) | POLBTNNI3KKAT6AL3MBTL1ALDH1A1 | |
| SCHEMBL21353640 | 0.77 | ADRB3 (0.41) | KAT6AL3MBTL1GAAMAPK1 | |
| SCHEMBL28737771 | 0.76 | ADRB3 (0.41) | KAT6AL3MBTL1ALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699189-A | Modulators of beta-3 adrenergic receptors useful for the treatment or prevention of heart failure and disorders associated therewith | 艾尼纳制药公司 | 2020-09-22 | — | — | CN | disclosed |